For laboratory research only · Not for human or veterinary use
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GLP3-R 20 mg research vial

OCN-GLP3R-20

GLP3-R

Retatrutide (LY3437943)

Triple-receptor agonist · GLP-1 + GIP + glucagon

Labeled quantity · 20 mg

Research-use boundary

For laboratory research only. Not for human or veterinary use. This page is educational and does not provide medical advice, dosing, preparation or administration guidance.

Overview

What it is

Retatrutide is an investigational single molecule designed to activate the GLP-1, GIP and glucagon receptors. It is being studied for obesity, type 2 diabetes and related metabolic complications.

The three pathways have complementary roles in appetite, glucose regulation and energy metabolism. Retatrutide remains investigational and has not been approved for consumer use.

Evidence

Research snapshot

In Lilly's Phase 3 TRIUMPH-1 study, the highest-dose efficacy estimand reported an average 28.3% body-weight reduction at 80 weeks in adults with obesity.

Earlier peer-reviewed Phase 2 research established proof of concept for this triple-receptor approach. Full Phase 3 publication and regulatory review remain important.

Reference

Product specifications

CompoundRetatrutide
Development codeLY3437943
ClassTriple hormone-receptor agonist
TargetsGIPR · GLP-1R · glucagon receptor
Clinical-trial routeSubcutaneous
Clinical-trial scheduleOnce weekly
Labeled quantity20 mg
Catalog referenceOCN-GLP3R-20

Primary sources

Read the research

Research summaries are informational and may not apply to this catalog material. Product identity, purity and suitability require independent verification.